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Novel Findings of Anti-cancer Property of Propofol

[ Vol. 18 , Issue. 2 ]

Author(s):

Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*   Pages 156 - 165 ( 10 )

Abstract:


Background: Propofol, a widely used intravenous anesthetic agent, is traditionally applied for sedation and general anesthesia.

Explanation: Recent attention has been drawn to explore the effect and mechanisms of propofol against cancer progression in vitro and in vivo. Specifically, the proliferation-inhibiting and apoptosis-inducing properties of propofol in cancer have been studied. However, the underlying mechanisms remain unclear.

Conclusion: This review focused on the findings within the past ten years and aimed to provide a general overview of propofol's malignance-modulating properties and the potential molecular mechanisms.

Keywords:

Propofol, anesthetic, general anesthesia, neoplasms, anti-cancer, malignance-modulating.

Affiliation:

Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032

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