The Postulated Mechanism of Action of Amygdalin (Vitamin B17) on Cancer Cells

Author(s):

Mohamed Ali El-Desouky, Abdelgawad Ali Fahmi* and Karima Mahmoud Nasraldin   Pages 894 - 899 ( 6 )

Abstract:

The current study demonstrates amygdalin’s (vitamin B17) postulated mechanism of action on cancer cells where it kills cells by selective toxicity, promotes apoptosis via cell cycle arrest, induces apoptosis via intrinsic cell death pathway (the mitochondria-initiated pathway), and enhances immunity. Thus, amygdalin can be considered a valuable natural cancer therapeutic agent. The toxicity of Amygdalin was reviewed. Moreover, solutions to avoid the cyanide poisoning have been proposed.

Keywords:

Amygdalin, vitamin B17, mechanism, caspase3, cytochrome c oxidase, p53.

Affiliation:

Graphical Abstract:

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